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 Diabetes and cholesterol

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كاتب الموضوعرسالة





نقاط : 100240
تاريخ الانضمام : 31/12/1969

Diabetes and cholesterol Empty
مُساهمةموضوع: Diabetes and cholesterol   Diabetes and cholesterol I_icon_minitimeالأحد أكتوبر 31, 2010 2:13 pm

The increase in cholesterol in the body a very common condition in patients with diabetes (over 70% of patients with type II diabetes have such an increase). And cholesterol is an important factor enters in the composition of membranes of living cells. And plays an important role in the formation of many of the basic material in the body, including hormones, testosterone and estrogen and progesterone, in addition to being essential in the installation of yellow material manufactured in the liver and stored in the gallbladder, in addition to other functions within the body. However, increased cholesterol or any disturbance or disruption in processing within the body, leading to serious problems and serious impact on human health and life. And cholesterol disorder interferes with many diseases have a direct relationship with diabetes and high blood pressure, low cholesterol The cumulative density (LDL) as well as triglycerides in arteries, especially coronary artery lead to deadly diseases such as hardening of the artery and myocardial infarction.

So I thought I had said something about cholesterol and its effects and its relevance to both diseases former, diabetes and high blood pressure, being one of the reasons that help to get complications, in addition to the methods of treatment without drugs suitable for treatment of the ill effects of cholesterol.

Cholesterol is a substance has the advantages of steroid-alcoholic fat, hence its name associated with disease, hardening of the arteries feeding the heart. There are several types of cholesterol, but what concerns us two two main cholesterol and low density (LDL), which is called bad cholesterol, "is sticking to the inner layer of the arteries feeding the heart," cholesterol and high density (HDL), which is called good cholesterol, "prevents the accumulation of bad cholesterol on the walls of the arteries of the heart. "

High-density cholesterol to total cholesterol is a critical factor in determining the seriousness of total cholesterol in the body on human health. If the ratio of good cholesterol (HDL) is equal to 0.3 of total cholesterol and more (a third of the almost total cholesterol), the sum of total cholesterol is not important in terms of health because the ratio of good cholesterol enough to prevent bad cholesterol from sticking to the arteries of the heart. The ratio of good cholesterol (HDL) normal is 45 mg / cm 3 in males, while this percentage in females is 60 mg / cm 3, and this explains the reason for the scarcity of disease, hardening of the arteries of females compared to males, is attributed to the hormone estrogen, which is maintained females in larger quantities than males, according to doctors, is the reason for the high proportion of good cholesterol in the body of women, with evidence that menopause is the point of demise of protection for females with regard to the possibility of exposure to disease, hardening of the arteries, it is known that menopause is the point where you start the process of lack of and diminished secretion of the hormone estrogen in females. And must be at least "good" cholesterol in the body of 25 mg / cm 3 in males, and not less than 45 mg / cm 3 in females.

Prevention and treatment of high cholesterol

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A healthy diet balanced with the reduction of animal fat (saturated fat) in addition to coconut oil and palm oil (saturated oil).
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Weight loss, whether through sports or diet or both, and the best combination of the two.
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Focus on eating complex carbohydrates, as well as foods rich in fiber and soluble in water, such as legumes, vegetables and fruits.
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Sport ongoing and appropriate.
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Control of stress and life's problems.

Drug therapy
There are several types of drugs used to treat high cholesterol levels and called Antipyrine cholesterol cholesterol-lowering medications or organizations fat Lipid - regulating drugs, which are as follows:

1.

Staten Statins:
Such as atorvastatin atorvastatin, and Srivastaten cerivastatin, and Vlovastaten fluvastatin, pravastatin and pravastatin, and Smvastatin simvastatin.

Be used as a therapeutic first for certain types of high cholesterol, the group operates to inhibit the enzyme controls the rate of manufacturing cholesterol in the body called HMG CoA reductase, thus reducing the level of cholesterol by reducing the speed of manufacturing cholesterol and increase the ability of the liver to get rid of bad cholesterol in the blood. Usually taken in the evening with dinner or at bedtime to take advantage of the fact that the body produces greater amounts of cholesterol for the night. This group is generally safe and tolerable for most patients, side effects of hazardous rare. Side effects of this group for muscular weakness, when you get to be consulting a doctor to replace or reduce the drug dose. This is the best group in the treatment of high cholesterol. This package is suitable for the treatment of diabetic patients with high blood pressure, but must be wary of low blood pressure when standing.

2.

Viberat Fibrates:
Bzafayprit such as bezafibrate, and Vinovyprit fenofibrate, and Jimphipprozhel gemfibrozil. This group reduce triglycerides significantly. And can reduce triglycerides by 50% and raise the level of good cholesterol by 10-25%. The cholesterol may rise or fall depending on the type of bug that is not treated. Symptom profiles are: simple disorders of the digestive system, there is the possibility that drugs affecting this group Mspbta muscle weakness in the muscle myopathy. It was noted there are some cases in which drugs interact with this group Groups drugs Asalafonail Joris Sulphonylureas, used in the treatment of diabetic patients.

3.

Resins or resins exchange ions Negative Anion-exchange resins:
Kolstibol such as colestipol, cholestyramine and cholestyramine. They are sometimes called intervals or insulators acids Yellow Bile acid sequestrates, because it is associated with bile acids in the intestine and prevent the re-absorption and that the liver converts more cholesterol to bile acids, thus reducing the level of cholesterol in the blood. Described this group usually with a statin to patients with coronary heart disease to increase impact and to obtain a higher proportion to reduce cholesterol up to 40%. But there must be a difference between a time period dealt with the drugs, because drugs of this group affect the absorption of drugs statin group.

Hinder the absorption of drugs of this group of fat soluble vitamins, so if it continues to be addressed for a long time may require the intake of vitamin A, D and K. Have few side effects because it does not suck usually, but may show symptoms of delay in the clotting of blood for bleeding due to vitamin K deficiency. Yuhz usually a period of time not less than 4 hours for other drugs in order to ensure the lack of access to interact with other medicines.

4.

Nicotine acid Nicotinic acid:
Such as niacin Niacin. Works to reduce the level of triglycerides by reducing the free fatty acids or free-free fatty acids. This medication may lead to the high level of sugar because of the lack of glucose tolerance glucose intolerance that the doses are large and may lead to worsening of gout gout. Property acipimax of nicotine acid derivatives is characterized by symptoms with fewer side but less effective in reducing fat.

5.

Natural medicines Neutraceuticals:
Possible benefit of fish oil-rich fish oils with Omega-3 marine triglycerides in cases of high blood fat, triglycerides. Believed that stimulates the body's followers, an alternative route to metabolize fat.


Patient education
The responsibility for the flags of each patient with regard to his condition satisfactory under the responsibility of the doctor, Viidah the most important with regard to these diseases and the meaning of their infection and will result in the case of neglect in addition to the risks of high Alchollstorl and triglycerides.

The patient must understand very well that the purpose of giving him this information is not to increase his fears, but hope that is committed to patient drug therapy and drug to achieve the purpose of treatment.

In addition to the task of the doctor treating the patient, Valseddle located also has a big job in explaining the impact of medication and side effects that can appear, and times to take the medicine in addition to the instructions and guidelines that must be provided to the patient, which should focus on medicine as well as to adapt the lifestyle to fit with disease and does not conflict with him.

The patient must always remember that it is always the parent in treatment, For himself the task of the care and preservation of his health, which is the first person responsible for himself.

The patient not to eat any treatment, drug or drug, without asking your doctor whether this treatment is commensurate with his health. May be the pharmacological treatment interact with medications taken by the patient, leading to a lack of access to appropriate treatment or increase the impact of the drug. In the case of the appearance of any bidder that does not exist previously should consult a physician to the possibility that the medicine is responsible.

Due to the fact that these diseases have no symptoms, and can be felt or touch it, but if levels rose very high. It is essential that the patient knows that the treatment does not have direct implications of the phenomenon can be felt, so emergence of some side effects, especially at the beginning of treatment, does not mean that treatment is not useful, it must be less demand for treatment. In addition to attention not to forget the time the medication or cut medication without consulting your doctor will have serious consequences.

Finally, we must remember that this patient's chronic diseases must co-exist with them, lifestyle modification and adaptation of commitment to suit the healthy life with these diseases
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Diabetes and cholesterol
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